Top Definition
1.To be high on stimulants like Meth or coke.
2.To work obsessively or compulsively on something.
3.To adjust something.
4.To be way wrong about something
1.He did 4 fat ass lines, hes tweakin hard
2.I was tweakin on my room for like 4 hours
3.I was just Tweakin the carb on my truck
4.you think the Boston Celtics are the best team ever..man your tweakin.
Steve_Juggernautによって 2006年04月28日(金)
Outside of your normal boundaries
Boy 1: "Which came first the chicken or the egg?"
Boy 2: "Boi, what the.."
Boy 1: "My fault I'm tweakin"
Giddyによって 2005年04月24日(日)
(v) To be high on amphetamine.
"We be tweakin, like every single weekend, we be tweekin."

"Last night I danced for 10 hours, I was tweakin hard."
saeedによって 2003年10月20日(月)
1) to be high on stimulant supplements(vitamins) or drugs.

2) to be hyperactive.
1) sugar, caffeine, monster drinks, sugar, earl gray tea, amphetamine, methamphetamine are examples of commonly used stimulants that can cause a person to be tweakin. They can become fast-moving, jittery and if on meth violently jumpy or shaky (trembling)

2) ADD/ADHD, natural high, sugar high, caffeine high can cause tweakin (hypetactivity) where you'll just be all over t he place moving fast.

when someone is hyperactive it doesnt mean they are under the influence of methamphetamine where meth high causes similar behaviour but is a different kind of hyper.
skaterjackによって 2006年10月06日(金)
Acting senseless or saying random things for no apparent reason or either under the influence of marijuana.
"Man, Janet is high and she tweakin' hard."
THA.ONEによって 2009年04月30日(木)
smoking meth
Dude he was tweakin' really bad
rollin_ballsによって 2009年02月24日(火)
when you buck on somebody or think somebody thinks youre always thinking about them.
that bitch was tweakin' on the haunting of conneticut she thank somebody always tryna haunt her ass.
pinkmonkeyによって 2009年08月29日(土)
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