1)Despite its original intentions, it is most often interpreted as "Stuff You" written in shorthand.
2)Intended to mean shut the f**k up.
Hey, stfu man.
Willy Johnsonによって 2003年11月04日(火)
Used to mean Shut the "F" up, also means Step the "F" up.
"If you think you are man enough, then STFU and prove it".(Reference to the phrase, "Cowboy up"). Of course both phrases are commonly used together.
"If you think you are man enough, then STFU (Step The "F" Up) and prove it, otherwise STFU (Shut The "F" Up) and sit your ass down".
Cable Kennによって 2006年02月24日(金)
Shortened Version of "Shut the Fuck up!" Used commonly by people in Britan and England, also on such things like AIM, MSN, and Yahoo Messenger.

Literally, they are telling you to bang that girl more quietly, producing less orgasms. Go bang that person who said STFU with a crowbar in the ass.
Guy: "STFU"
Guy 2: "You go fuck it, or I shove a crowbar up yo hole!"
Guy: "What? Go Rape a bus!"
W/eによって 2005年03月09日(水)
1. An abbreviation for Shut The Fuck Up.

2. An abbreviation for STupid FUcker
STFU n00b stop being gay.
vipa!!!によって 2005年11月04日(金)
Meaning: Shut The Fuck Up! used when instant messaging
Used in the IMing world: "You stupid bitch!....STFU"
Kirsti... yo.によって 2006年04月20日(木)
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