Top Definition
Coined in Lanipator's Yu Yu Hakusho Abridged. Piccoloitis is a very rare ailment that causes normally evil people to change their ways, and care about something weaker than them, like Piccolo cares about Gohan in Dragonball Z.
Kurama in Yu Yu Hakusho Abridged has Piccoloitis. He cares deeply for his adoptive human mother even though he is an evil demon
Sure is Zarbon in Hereによって 2011年02月02日(水)

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